seqCBS: Copy Number Profiling using Sequencing and CBS

This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.

Version: 1.2.1
Depends: R (≥ 2.10), clue
Published: 2019-04-13
Author: Jeremy J. Shen, Nancy R. Zhang
Maintainer: Jeremy J. Shen <jeremyjshen at>
License: GPL-2
NeedsCompilation: yes
CRAN checks: seqCBS results


Reference manual: seqCBS.pdf


Package source: seqCBS_1.2.1.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): seqCBS_1.2.1.tgz, r-oldrel (arm64): seqCBS_1.2.1.tgz, r-release (x86_64): seqCBS_1.2.1.tgz
Old sources: seqCBS archive


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